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TG6-10-1

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SI-6762

TG6-10-1, >98% (HPLC)

CAS No. : [1415716-58-3]

IUPAC Name : (E)-N-(2-(2-(Trifluoromethyl)-1H-indol-1-yl)ethyl)-3-(3,4,5-trimethoxyphenyl)acrylamide

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Chemical Properites
Mol. Formula :
C23H23F3N2O4
Mol. Weight :
448.44
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : TG6‑10‑1 selectively blocks EP2 with low‑nanomolar potency and demonstrates strong receptor selectivity, showing >300‑fold discrimination against EP3, EP4, and IP receptors and ~100‑fold against EP1. It is a valuable tool for studying EP2‑specific biological pathways.

References : Jiang J. et al.: Proc. Natl. Acad. Sci. U. S. A., 110(9), 3591-3596, 2013; Kang. X. et al.: Sci. Rep., 7(1), 9459, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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