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TH-257

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SI-7199

TH-257, >98% (HPLC)

CAS No. : [2244678-29-1]

IUPAC Name : N-Benzyl-N-butyl-4-(N-phenylsulfamoyl)benzamide

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Chemical Properites
Mol. Formula :
C24H26N2O3S
Mol. Weight :
422.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : TH‑257 is a potent, highly selective allosteric LIMK1/2 inhibitor (IC50 = 84/39 nM) with no detectable kinome off‑targets at 1 µM.

References : Manetti F. et al.: Eur. J. Med. Chem., 155, 445-458, 2015; Collins R. et al.: J. Med. Chem., 65(20), 13705-13713, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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