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Thioridazine 2-sulfone-d3

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SI-6570

Thioridazine 2-sulfone-d3, >98% (HPLC)

CAS No. : [1329652-09-6]

IUPAC Name : 10-(2-(1-(Methyl-d3)piperidin-2-yl)ethyl)-2-(methylsulfonyl)-10H-phenothiazine

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Chemical Properites
Mol. Formula :
C21H23D3N2O2S2
Mol. Weight :
405.59
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Thioridazine‑d3 2‑sulfone is a deuterium-labelled version of Thioridazine analog. Thioridazine inhibits D2 receptors and PI3K–Akt–mTOR signaling and selectively targets CSCs.

References : Russak E. M. et al.: Ann. Pharmacother., 53(2), 211-216, 2019; Tschanz J. T. et al.: Pharmacol. Biochem. Behav., 31(3), 519-22, 1988; Mu J. et al.: Oncol. Rep., 31(5), 2107-14, 2014; Aguilar-Vega L. et al.: J. Appl. Microbiol., 131(5), 2235-2243, 2021; Kang S. et al.: Apoptosis., 17(9), 989-97, 2012; Loehr A. R. et al.: Cancers (Basel)., 13(9), 2045, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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