THZ1-(R)

SI-5950

THZ1-(R), >98% (HPLC)

CAS No. : [1621523-07-6]

MDL No. : MFCD29924746

IUPAC Name : N-(3-((5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)butanamido)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : THZ1-R is a non-cysteine reactive analog of THZ1, which is a elective and potent covalent CDK7 inhibitor in the development of potential cancer therapy drug.

References : Kwiatkowski N. et al.: Nature 511(7511), 616-20, 2014; Zeng M. et al.: Elife 7, pii: e39030, 2018; Christensen C. L. et al.: Cancer Cell 26(6), 909-22, 2014; Chipumuro E. et al.: Cell 159(5), 1126-39, 2014; Jiang Y-Y. et al.: Gut., 66(8), 1358-1368, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.