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Tipiracil

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SI-6143

Tipiracil, >98% (HPLC)

CAS No. : [183204-74-2]

IUPAC Name : 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione

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Chemical Properites
Mol. Formula :
C9H11ClN4O2
Mol. Weight :
242.66
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Tipiracil selectively inhibits thymidine phosphorylase, blocking thymidine degradation and modulating angiogenesis‑related pathways. It is commonly employed to improve trifluridine exposure and antitumor efficacy.

References : Lee S. J. et al.: Eur. J. Nucl. Med. Mol. Imaging, 41(7), 1327-35, 2014; Raedler L. A.: Am.Health Drug Benefits, 9(Spec Feature), 97-100, 2016; Tanaka N. et al.: Oncol. Rep., 32(6), 2319-26, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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