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Tipranavir

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SI-5899

Tipranavir, >98% (HPLC)

CAS No. : [174484-41-4]

MDL No. : MFCD00949098

Synonyms : PNU-140690

IUPAC Name : N-(3-((R)-1-((R)-4-Hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)propyl)phenyl)-5-(trifluoromethyl)pyridine-2-sulfonamide

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Chemical Properites
Mol. Formula :
C31H33F3N2O5S
Mol. Weight :
602.67
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Tipranavir is the first nonpeptidic protease inhibitor used for the treatment of drug-resistant HIV infection. Tipranavir is also a SARS-CoV-2 3CLpro inhibitor for the potential treatment of COVID-19.

References : Aoki M. et al.: J. Virol., 86(24), 13384-96, 2012; Li F. et al.: Drug Metab Dispos., 38(5), 871-8, 2010; Sun Q. et al.: Signal Transduct Target Ther. 6(1), 212, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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