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Tivozanib-d6 hydrochloride

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SL-10040

Tivozanib-d6 hydrochloride, >98%

Related CAS No. : [2211146-40-4] of the unlabelled compound

IUPAC Name : 1-(4-((6,7-Bis(methoxy-d3)quinolin-4-yl)oxy)phenyl)-3-(5-methylisoxazol-3-yl)urea hydrochloride

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Chemical Properites
Mol. Formula :
C22H14D6N4O5 • HCl
Mol. Weight :
462.92
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Tivozanib, which is a highly potent and selective VEGFR 1/2/3 inhibitor. Tivozanib can be used for the treatment of relapsed or refractory advanced renal cell carcinoma.

References : Nakamura K. et al.: Cancer Res., 66(18), 9134-9142, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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