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Tizoxanide-d4

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SL-6104

Tizoxanide-d4, >98% (CP)

Isotopic Purity : 98 atom % D

CAS No. : [1246817-56-0]

MDL No. : MFCD15071359

Synonyms : Desacetyl nitazoxanide-d4; NSC 697856-d4; TIZ-d4

IUPAC Name : 2-Hydroxy-N-(5-nitrothiazol-2-yl)benzamide-d4

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Chemical Properites
Mol. Formula :
C10H3D4N3O4S
Mol. Weight :
269.27
Appearance :
Brown solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Tizoxanide-d4 is a deuterium labelled version of Tizoxanide. It is a thiazolide anti-infective, and an active against anaerobic bacteria, protozoa, and a range of viruses in cell culture models. Tizoxanide is currently in phase II clinical development for treating chronic hepatitis C. Also, this is a COVID-19 related research chemical.

References : Theodos C. M. et al.: Antimicrob Agents Chemother., 42(8), 1959-1965, 1998; Fox L. M. et al.: Clin Infect Dis., 40(8), 1173-1180, 2005; Adagu I. S. et al.: J. Antimicrob Chemother., 49(1), 103-111, 2002; Korba B. E. et al. Antiviral Res., 77(1), 56-63, 2008; Cedillo-Rivera R. et al.: J. Eukaryot Microbiol., 49(3), 201-208, 2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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