TKB-248

SI-7386

TKB-248, >98% (HPLC)

CAS No. : [2892688-17-2]

IUPAC Name : 2,2,2-Trifluoro-N-((S)-1-((1R,2S,5S)-2-(((S)-1-(4-fluorobenzo[d]thiazol-2-yl)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)carbamothioyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-3-yl)-3,3-dimethyl-1-oxobutan-2-yl)acetamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : TKB-248 selectively targets the SARS‑CoV‑2 Mpro enzyme with an IC₅₀ of 74 nM and shows robust antiviral potency, reducing SARS‑CoV‑2 replication with EC₅₀ and EC₉₅ values of 0.22 µM and 0.87 µM. Its profile highlights its value as a tool compound for studying coronavirus protease inhibition.

References : Higashi-Kuwata N. et al.Nat. Commun., 14(1), 1076, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.