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Tofacitinib amide impurity

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Tofacitinib amide impurity, >98%

CAS No. : [1675248-19-7]

IUPAC Name : 3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG85.00
In Stock  Estimated to ship on 20 September 2026
10MG135.00
In Stock  Estimated to ship on 20 September 2026
25MG255.00
In Stock  Estimated to ship on 20 September 2026
50MG455.00
In Stock  Estimated to ship on 20 September 2026
100MG755.00
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C16H22N6O2
Mol. Weight :
330.39
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an amide impurity of Tofacitinib, which is a potent, specific, orally active JAK3 inhibitor. Tofacitinib is used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. This is also a COVID-19 related research chemical.

References : Changelian P. S. et al.: Science 302(5646), 875-888, 2003; Jiang J. K. et al.: J. Med. Chem., 51(24), 8012-8018, 2008; Kudlacz E. et al.: Am. J. Transplant., 4(1) 51-57, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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