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Tofacitinib benzyl analog

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Tofacitinib benzyl analog, >98%

CAS No. : [477600-73-0]

IUPAC Name : N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G65.00
In Stock  Estimated to ship on 20 September 2026
5G225.00
In Stock  Estimated to ship on 20 September 2026
10G395.00
In Stock  Estimated to ship on 20 September 2026
25G795.00
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C20H25N5
Mol. Weight :
335.45
Appearance :
Pale beige solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a benzyl analog / impurity of Tofacitinib, which is a potent, specific, orally active JAK3 inhibitor. Tofacitinib is used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. This is also a COVID-19 related research chemical.

References : Changelian P. S. et al.: Science 302(5646), 875-888, 2003; Jiang J. K. et al.: J. Med. Chem., 51(24), 8012-8018, 2008; Kudlacz E. et al.: Am. J. Transplant., 4(1) 51-57, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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