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Tofacitinib-d3

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SL-9012

Tofacitinib-d3, >98%

Related CAS No. : [477600-75-2] of the unlabelled compound

Synonyms : Tasocitinib-d3; CP-690550-d3

IUPAC Name : 3-((3R,4R)-4-Methyl-3-((methyl-d3)(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C16H17D3N6O
Mol. Weight :
315.40
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium-labelled version of Tofacitinib, which is a potent, specific, orally active JAK3 inhibitor. Tofacitinib is used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. This is also a COVID-19 related research chemical.

References : Changelian P. S. et al.: Science 302(5646), 875-888, 2003; Jiang J. K. et al.: J. Med. Chem., 51(24), 8012-8018, 2008; Kudlacz E. et al.: Am. J. Transplant., 4(1) 51-57, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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