Tofacitinib N-nitroso impurity 1

SL-9022

Tofacitinib N-nitroso impurity 1, >98%

IUPAC Name : N-((3R,4R)-1-(2-Cyanoacetyl)-4-methylpiperidin-3-yl)-N-methylnitrous amide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is a nitrosamine impurity of Tofacitinib, which is a potent, specific, orally active JAK3 inhibitor. Tofacitinib is used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. This is also a COVID-19 related research chemical.

References : Changelian P. S. et al.: Science 302(5646), 875-888, 2003; Jiang J. K. et al.: J. Med. Chem., 51(24), 8012-8018, 2008; Kudlacz E. et al.: Am. J. Transplant., 4(1) 51-57, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.