Tolebrutinib

SI-6289

Tolebrutinib, >98% (HPLC)

CAS No. : [1971920-73-6]

Synonyms : SAR-442168; PRN-2246

IUPAC Name : (R)-1-(1-Acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Tolebrutinib is a brain‑penetrant BTK inhibitor with sub‑nanomolar potency in B cells and microglia. Its ability to modulate CNS immune pathways underlies its relevance in mechanistic and therapeutic studies of multiple sclerosis.

References : Dahl K. et al.: J. Labelled Comp Radiopharm., 63(11), 482-487, 2020; Francesco M. R. et al.: Multiple Sclerosis Journal., Poster Session 2, P989, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.