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Tolvaptan

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SI-2753

Tolvaptan, >98% (HPLC)

CAS No. : [150683-30-0]

MDL No. : MFCD09837707

Synonyms : OPC-41061

IUPAC Name : N-(4-(7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

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Chemical Properites
Mol. Formula :
C26H25ClN2O3
Mol. Weight :
448.94
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation.

References : Liu K. K-C. et al.: Bioorg. Med. Chem., 19(3), 1136-1154, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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