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Torcetrapib

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SI-6774

Torcetrapib, >98% (HPLC)

CAS No. : [262352-17-0]

Synonyms : CP-529414

IUPAC Name : Ethyl (2R,4S)-4-((3,5-bis(trifluoromethyl)benzyl)(methoxycarbonyl)amino)-2-ethyl-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2H)-carboxylate

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Chemical Properites
Mol. Formula :
C26H25F9N2O4
Mol. Weight :
600.48
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Torcetrapib selectively inhibits CETP with high potency and displays a characteristic inhibition profile in whole human plasma containing 37 nM CETP. Its activity makes it a valuable tool for studying CETP‑mediated lipid transfer.

References : Ronald W. Clark. et al.: Arterioscler. Thromb. Vasc. Biol., 24(3), 490-7, 2004; Luke Esau. et al.: Genes Cancer., 7(9-10), 309-322, 2016; Michael K. Hansen. et al.: J. Cardiovasc. Pharmacol. Ther., 15(2), 196-202, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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