Torin 1

SI-6331

Torin 1, >98% (HPLC)

CAS No. : [1222998-36-8]

IUPAC Name : 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Torin 1 potently inhibits mTOR at low‑nanomolar concentrations and blocks both mTORC1‑ and mTORC2‑dependent signaling. Its strong autophagy‑inducing activity makes it a valuable tool for probing mTOR‑regulated cellular processes.

References : Thoreen C. C, et al.: J. Biol. Chem., 284(12), 8023-8032, 2009; Liu Q. et al.: J. Med. Chem., 53(19), 7146-55, 2010; Bi C. et al.: Haematologica., 102(4), 755-764, 2017; Brandt M. et al.: Cell Metab., 27(1), 118-135.e8, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.