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CAS No. : [1092351-67-1]
Synonyms : PP-242
IUPAC Name : 2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C16H16N6O | Mol. Weight : 308.35 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Torkinib inhibits mTOR with high potency (IC50 = 8 nM) in an ATP‑competitive manner and blocks both mTORC1 and mTORC2 signaling (IC50 = 30 nM and 58 nM). Its dual‑complex inhibition profile supports its use in mechanistic studies of mTOR‑regulated cellular processes.
References : Apsel B. et al.: Nat. Chem. Biol., 4(11), 691-9, 2008; Feldman M. E. et al.: PLoS Biol., 7(2), e38, 2009.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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