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TPA-023

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SI-5055

TPA-023, >98% (HPLC)

CAS No. : [252977-51-8]

MDL No. : MFCD29921350

Synonyms : MK-0777; L-830982

IUPAC Name : 7-(tert-Butyl)-6-((1-ethyl-1H-1,2,4-triazol-5-yl)methoxy)-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine

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Chemical Properites
Mol. Formula :
C20H22FN7O
Mol. Weight :
395.44
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : TPA-023 is a GABAA α2/α3 subtype-selective agonist, for the potential treatment of schizophrenia.

References : Atack J. R. et al.: Adv Pharmacol., 57, 137-85, 2009; Castner S. A. et al.: Biol Psychiatry., 67(10), 998-1001, 2010; Rajagopal L. et al.: Neuropsychopharmacology 43(12), 2468-2477, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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