Trametinib

SI-3991

Trametinib, >98% (HPLC)

CAS No. : [871700-17-3]

MDL No. : MFCD17215075

Synonyms : GSK-1120212; JTP-74057

IUPAC Name : N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	335.00		Back Order	Estimated to ship on 04 October 2026
5G	995.00		Back Order	Estimated to ship on 04 October 2026
10G	1595.00		Back Order	Estimated to ship on 04 October 2026
25G	3095.00		Back Order	Estimated to ship on 04 October 2026

Applications : Trametinib is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2.

References : Ding X. H. et al.: Bioorg. Med. Chem. 23(9), 1895-1922, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.