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Trametinib cyclopropylamide impurity

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Trametinib cyclopropylamide impurity, >98%

CAS No. : [3018911-27-5]

IUPAC Name : N-Cyclopropyl-2-((2-fluoro-4-iodophenyl)amino)-4-hydroxy-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide

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Chemical Properites
Mol. Formula :
C17H17FIN3O3
Mol. Weight :
457.24
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Trametinib, which is a highly specific and potent MEK1/2 inhibitor. Trametinib is used to treat specific types of cancers that have a (BRAF) V600 gene mutation.

References : Ding X. H. et al.: Bioorg. Med. Chem. 23(9), 1895-1922, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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