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trans-Hydrazide

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trans-Hydrazide, >98%

CAS No. : [1821721-62-3]

Synonyms : Tranylcypromine impurity D

IUPAC Name : (1R, 2R)-2-Phenylcyclopropane-1-carbohydrazide-rel; trans-2-Phenylcyclopropanecarboxylic hydrazide

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Chemical Properites
Mol. Formula :
C10H12N2O
Mol. Weight :
176.22
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Tranylcypromine, which is an irreversible inhibitor of monoamine oxidase (MAO) with a rapid onset of activity. It is used as an antidepressant and anxiolytic agent in the clinical treatment of mood and anxiety disorders.

References : Zhang W. et al.: Drug Metab Dispos., 29(6), 897-902, 2001; Hong S. L. et al.: J. Biol. Chem., 255(20), 9538-9540, 1980; Taavitsainen P. et al.: Drug Metab Dispos., 29(3), 217-222, 2001; Negishi T. et al. Environ Health Perspect., 112(11), 1159-1164, 2004; Ji Y. Y. et al. Eur. J. Med Chem., 141, 101-112, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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