trans-PX-20606

SI-7908

trans-PX-20606, >98% (HPLC)

CAS No. : [1268244-85-4]

Synonyms : trans-PX-102

IUPAC Name : 4-((1R,2R)-2-(2-Chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)phenyl)cyclopropyl)benzoic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : PX-20606 trans racemate activates FXR with low‑nanomolar potency, showing EC₅₀values of 32 nM (FRET) and 34 nM (M1H). Its robust activity across orthogonal assay systems supports its use in studies of FXR‑dependent bile‑acid and metabolic signaling.

References : Kinzel O. et al.: Bioorg. Med. Chem. Lett., 26(15), 3746-53, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.