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Trazodone hydrochloride

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SL-10051

Trazodone hydrochloride, >98%

CAS No. : [25332-39-2]

Synonyms : AF-1161

IUPAC Name : 2-(3-(4-(3-Chlorophenyl)piperazin-1-yl)propyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one hydrochloride

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25MGRequest A Quote
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Chemical Properites
Mol. Formula :
C19H22ClN5O • HCl
Mol. Weight :
408.33
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Trazodone is a triazolopyridine derivative that belongs to the class of serotonin receptor antagonist and reuptake inhibitors (SARIs). It exhibits both antidepressant and anti-insomnia effects. Trazodone functions primarily by antagonising α1- and α2-adrenergic receptors as well as histamine H1 receptors, while demonstrating minimal anticholinergic activity.

References : Fagiolini A. et al.: CNS Drugs 26(12), 1033-49, 2012; Raffa R. B. et al.: Psychopharmacology, 108(3), 320-326, 1992; Ghanbari R. et al.: The Journal of pharmacology and experimental therapeutics, 335(1), 197-206, 2010; Jay A. R. et al.: Am J. Vet Res., 74(11), 1450-6, 2013; Daniele S. et al.: Cell Signal., 27(8), 1609-29, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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