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Trelagliptin amide impurity

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Trelagliptin amide impurity, >98%

CAS No. : [1938080-44-4]

IUPAC Name : (R)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzamide

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Chemical Properites
Mol. Formula :
C18H22FN5O3
Mol. Weight :
375.4
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Trelagliptin, which is a long-acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D).

References : Flick C. A. et al.: J. Med. Chem., 60(15), 6480-6515, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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