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Triazolomethylindole-3-acetic acid

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SL-7722

Triazolomethylindole-3-acetic acid, >98%

CAS No. : [177270-91-6]

IUPAC Name : 5-(1H-1,2,4-Triazol-1-ylmethyl)-1H-indole-3-acetic acid

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Chemical Properites
Mol. Formula :
C13H12N4O2
Mol. Weight :
256.27
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a metabolite of Rizatriptan, which is an agonist at serotonin 5-HT1B and 5-HT1D receptors. It is used to treat acute migraine attacks.

References : Williamson D. J. et al.: Br. J. Pharmacol., 133(7), 1029-1034,2001; Williamson D. J. et al.: Eur J. Pharmacol., 328(1), 61-64,1997; Yao G. et al.: Neural Regen Res., 7(2), 131-135,2012; Wang X. et al.: Brain Res., 1367, 340-346,2011; Dong Z. et al.: Brain Res., 1368, 151-158,2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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