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Trifluoperazine sulfone

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Trifluoperazine sulfone, >98%

CAS No. : [2230802-07-8]

IUPAC Name : 10-(3-(4-Methylpiperazin-1-yl)propyl)-2-(trifluoromethyl)-10H-phenothiazine 5,5-dioxide

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Chemical Properites
Mol. Formula :
C21H24F3N3O2S
Mol. Weight :
439.5
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity or metabolite of Trifluoperazine, which is an antipsychotic that blocks central dopamine receptors, inhibits α1-adrenergic receptors, NUPR1, calmodulin, and P-glycoprotein, and acts as a reversible inhibitor of influenza virus morphogenesis. Trifluoperazine is used in schizophrenia research and has anticancer properties.

References : Huerta-Bahena J. et al.: Mol Pharmacol., 23(1), 67-70, 1983; Santofimia-Castaño P, et al.: J. Clin Invest., 129(6), 2500-2513, 2019; Marques L.O. et al.: Cochrane Database Syst Rev., 2004(1), CD003545, 2004; Howland R. H. J. Psychosoc Nurs Ment Health Serv., 54(1), 20-22, 2016; Ochiai H. et al.: Antiviral Res., 15(2), 149-160, 1991.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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