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Trilaciclib impurity 5

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Trilaciclib impurity 5, >98%

CAS No. : [2170746-99-1]

IUPAC Name : tert-Butyl 2'-(methylthio)-6'-oxo-6'H-spiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidine]-7'(8'H)-carboxylate

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Chemical Properites
Mol. Formula :
C20H26N4O3S
Mol. Weight :
402.51
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Trilaciclib, which is an oral CDK4/6 inhibitor that effectively suppresses tumour cell proliferation and helps reduce the blood-related toxicity associated with chemotherapy. Additionally, Trilaciclib lessens both apoptosis and myelosuppression caused by 5-Fluorouracil (5-FU) chemotherapy.

References : Bisi J. E. et al.: Mol Cancer Ther., 15(5), 783-93, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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