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TRPA1-IN-1

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SI-6516

TRPA1-IN-1, >98% (HPLC)

CAS No. : [2376824-92-7]

IUPAC Name : 1-((3-((3R,5R)-5-(4-Chlorophenyl)tetrahydrofuran-3-yl)-1,2,4-oxadiazol-5-yl)methyl)-7-methyl-1,7-dihydro-6H-purin-6-one

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Chemical Properites
Mol. Formula :
C19H17ClN6O3
Mol. Weight :
412.83
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : A potent, selective, and orally bioavailable TRPA1 small‑molecule antagonist suitable for use in neuropathic pain research and respiratory disease models, including asthma and chronic cough.

References : Terrett A. J. et al.: J. Med. Chem., 64(7), 3843−3869, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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