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TTP-273

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SI-8069

TTP-273, >98% (HPLC)

IUPAC Name : (2S)-2-((8S)-3-(4-((3,4-Dichlorobenzyl)oxy)phenyl)-7-((S)-1-phenylpropyl)-2,3,6,7,8,9-hexahydro-[1,4]dioxino[2,3-g]isoquinoline-8-carboxamido)-3-(4-(2,3-dimethylpyridin-4-yl)phenyl)propanoic acid

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C50H47Cl2N3O6
Mol. Weight :
856.84
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : TTP‑273 is an orally active small‑molecule GLP‑1 receptor agonist that stimulates GLP‑1R‑mediated cAMP signaling to support glucose lowering, appetite suppression, and metabolic regulation. As a non‑peptide agonist, it represents a key advance toward oral GLP‑1R therapeutics for type 2 diabetes and obesity.

References : Chen L. et al.: : J. Med. Chem., 66(12), 7988-8010, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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