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Turofexorate isopropyl

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SI-6016

Turofexorate isopropyl, >98% (HPLC)

CAS No. : [629664-81-9]

MDL No. : MFCD13181507

Synonyms : WAY-362450; FXR-450; XL-335

IUPAC Name : Isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate

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25MGRequest A Quote
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We accept
Chemical Properites
Mol. Formula :
C25H24F2N2O3
Mol. Weight :
438.47
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Turofexorate isopropyl is a highly potent, selective, and orally active agonist of the farnesoid X receptor (FXR), plays a critical role in the regulation of bile acid, triglyceride (TG), and cholesterol homeostasis.

References : Flatt B. et al.: J. Med. Chem., 52(4), 904-7, 2009; Evans M. J. et al.: Am. J. Physiol Gastrointest Liver Physiol., 296(3), G543-52, 2009; Hartman H. B. et al.: J. Lipid Res., 50(6), 1090-100, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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