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CAS No. : [133550-30-8]
MDL No. : MFCD00236452
Synonyms : AG 490
IUPAC Name : (2E)-N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | 25.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 100MG | 85.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 250MG | 195.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 500MG | 355.00 | In Stock | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C17H14N2O3 | Mol. Weight : 294.30 |
Appearance : Yellow solid | Melting Point : 217-218oC |
Solubility : DMSO | |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : The tyrphostin B42 inhibits cell proliferation and HER-2 autophosphorylation in cervical carcinoma cell lines. It is a selective inhibitor of EGF-receptor tyrosine kinase. Inhibitor of JAK2 JAK3/STAT, JAK3/AP-1 and JAK3/MAPK pathways.
References : Cruz. S. et. al.: Cancer Invest., 26(2),136, 2008.
Storage : Store at RT
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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