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Ubrogepant

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SL-10057

Ubrogepant, >98%

CAS No. : [1374248-77-7]

Synonyms : MK-1602

IUPAC Name : (S)-N-((3S,5S,6R)-6-Methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C29H26F3N5O3
Mol. Weight :
549.55
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Ubrogepant is an orally active, selective antagonist of the calcitonin gene-related peptide receptor (CGRP). It demonstrates a strong binding affinity for CGRP receptors in both humans and rhesus monkeys, and inhibits the cAMP response induced by α-CGRP. Ubrogepant is utilized in research related to acute migraine.

References : Moore E. et al.: J. Pharmacol Exp Ther., 119, 261065, 2020; Li C. C. et al.: J. Clin Pharmacol., 58(3), 294-303, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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