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UC-1728

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SI-7698

UC-1728, >98% (HPLC)

CAS No. : [948304-40-3]

Synonyms : t-TUCB

IUPAC Name : 4-(((1r,4r)-4-(3-(4-(Trifluoromethoxy)phenyl)ureido)cyclohexyl)oxy)benzoic acid

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Chemical Properites
Mol. Formula :
C21H21F3N2O5
Mol. Weight :
438.4
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : UC‑1728 potently inhibits rabbit soluble epoxide hydrolase, with an IC50 of 2 nM measured in rabbit liver tissue. It is widely used to investigate sEH‑dependent signaling and the biological roles of epoxyeicosatrienoic acids.

References : Mc Lellan G. J. et al.: J. Ocul. Biol., 4(1), 2016; Shrestha A. et al.: J. Pharm Pharmacol., 66(9), 1251-8, 2014; Guedes A. G. et al.: Vet. Anaesth. Analg., 40(4), 440-8, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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