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UCM-05194 ammonium

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SI-7643

UCM-05194 ammonium, >98% (HPLC)

IUPAC Name : Ammonium (S)-3-bromo-2-((10-phenyldecanoyl)oxy)propyl hydrogen phosphate

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Chemical Properites
Mol. Formula :
C19H29BrO6P- • +NH4
Mol. Weight :
482.35
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : UCM‑05194 ammonium activates the LPA1 receptor with sub‑micromolar potency (EC50= 0.24 µM), triggering calcium signaling in RH7777 cells. It induces neurite retraction and migration in LPA1‑overexpressing B103 cells and reduces nociceptive behaviors in mouse pain models, highlighting its value for probing LPA1‑regulated neuronal and sensory pathways.

References : Gil I. G. et al.: J. Med. Chem., 63(5), 2372-2390, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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