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UM-164

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SI-6252

UM-164, >98% (HPLC)

CAS No. : [903564-48-7]

Synonyms : DAS-DFGO-II

IUPAC Name : 2-((6-(4-(2-Hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)thiazole-5-carboxamide

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Chemical Properites
Mol. Formula :
C30H31F3N8O3S
Mol. Weight :
640.69
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : UM‑164 is a dual‑acting kinase inhibitor with strong potency against c‑Src (K_d = 2.7 nM) and robust inhibitory activity toward p38α and p38β. It is widely used to probe Src/MAPK‑mediated cellular processes.

References : Gilani R. A. et al.: Clin. Cancer Res., 22(20), 5087-5096, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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