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UNC-2881

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SI-6398

UNC-2881, >98% (HPLC)

CAS No. : [1493764-08-1]

IUPAC Name : N-(4-(1H-Imidazol-1-yl)benzyl)-2-(butylamino)-4-(((1r,4r)-4-hydroxycyclohexyl)amino)pyrimidine-5-carboxamide

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Chemical Properites
Mol. Formula :
C25H33N7O2
Mol. Weight :
463.59
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : UNC-2881 selectively targets Mer kinase with low‑nanomolar potency and shows moderate inhibition of Axl and Tyro3. It strongly suppresses collagen‑induced platelet aggregation, supporting its use in dissecting TAM‑kinase signaling pathways and thrombosis biology.

References : Zhang W. et al.: J. Med. Chem., 56(23), 9693-700, 2013; Tom Adomati. et al.: Cell Reports, 30(11), 3671-3681, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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