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Upadacitinib

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SI-1066

Upadacitinib, >98% (HPLC)

CAS No. : [1310726-60-3]

MDL No. : MFCD30502663

Synonyms : ABT-494

IUPAC Name : (3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG75.00
In Stock  Estimated to ship on 20 September 2026
10MG125.00
In Stock  Estimated to ship on 20 September 2026
25MG255.00
In Stock  Estimated to ship on 20 September 2026
50MG455.00
In Stock  Estimated to ship on 20 September 2026
100MG855.00
In Stock  Estimated to ship on 20 September 2026
250MG1655.00
In Stock  Estimated to ship on 20 September 2026
500MG2655.00
In Stock  Estimated to ship on 20 September 2026
We accept
Chemical Properites
Mol. Formula :
C17H19F3N6O
Mol. Weight :
380.37
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Upadacitinib (ABT-494) is a potent and selective Janus kinase (JAK) 1 inhibitor with an IC50 of 43 nM, being developed for the treatment of several autoimmune disorders.

References : Genovese M. C. et al.: Arthritis Rheumatol., 68(12), 2857-2866, 2016; Kremer J. M. et al.: Arthritis Rheumatol., 68(12), 2867-2877, 2016; Mohamed M. F. et al.: Clin Pharmacokinet., 55(12), 1547-1558, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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