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CAS No. : [1310726-60-3]
MDL No. : MFCD30502663
Synonyms : ABT-494
IUPAC Name : (3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | 75.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 10MG | 125.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 25MG | 255.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 50MG | 455.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 100MG | 855.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 250MG | 1655.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 500MG | 2655.00 | In Stock | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C17H19F3N6O | Mol. Weight : 380.37 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Upadacitinib (ABT-494) is a potent and selective Janus kinase (JAK) 1 inhibitor with an IC50 of 43 nM, being developed for the treatment of several autoimmune disorders.
References : Genovese M. C. et al.: Arthritis Rheumatol., 68(12), 2857-2866, 2016; Kremer J. M. et al.: Arthritis Rheumatol., 68(12), 2867-2877, 2016; Mohamed M. F. et al.: Clin Pharmacokinet., 55(12), 1547-1558, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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