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Uprosertib

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SI-5287

Uprosertib, >98% (HPLC)

CAS No. : [1047634-65-0]

MDL No. : MFCD28144686

Synonyms : GSK-2141795

IUPAC Name : (S)-N-(1-Amino-3-(3,4-difluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)furan-3-carboxamide

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C18H16Cl2F2N4O2
Mol. Weight :
429.25
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Uprosertib is a potent and selective pan-AKT inhibitor with IC50 values of 180/328/38 nM for AKT1/AKT2/AKT3, respectively.

References : Pachl F. et al.: J. Proteome Res., 12(8), 3792-800, 2013; Jacobsen K. et al.: Nat Commun., 8(1), 410, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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