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CAS No. : [2455519-86-3]
Synonyms : ZYIL-1
IUPAC Name : (R,E)-2-(1,2-Dimethylpyrrolidin-2-yl)-N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)ethene-1-sulfonamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C21H29N3O3S | Mol. Weight : 403.54 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Usnoflast selectively targets the NLRP3 inflammasome and is orally active, effectively blocking IL‑1β secretion and attenuating downstream inflammatory signaling. Its pharmacological profile supports its use in mechanistic studies of NLRP3‑mediated inflammation.
References :
Chatterjee A. et al.: Brain Res., 1842, 149129, 2024.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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