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UT-155

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SI-7277

UT-155, >98% (HPLC)

CAS No. : [2031161-35-8]

IUPAC Name : (S)-N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-(5-fluoro-1H-indol-1-yl)-2-hydroxy-2-methylpropanamide

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Chemical Properites
Mol. Formula :
C20H15F4N3O2
Mol. Weight :
405.35
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : UT‑155 is a selective and potent androgen receptor (AR) antagonist with a Ki of 267 nM for binding to the AR ligand‑binding domain (AR‑LBD). UT‑155 effectively blocks AR signaling and serves as a useful tool compound for studying AR‑dependent pathways in prostate cancer and other androgen‑driven biological systems.

References : Ponnusamy S. et al.: Cancer Res., 77(22), 6282-6298, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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