Valganciclovir N-valyl impurity

SL-10663

Valganciclovir N-valyl impurity, >98%

CAS No. : [897937-73-4]

Synonyms : L-Valyl-L-valine 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydro xypropyl ester; N-(L-Valyl) Valganciclovir hydrochloride; Valganciclovir amide diastereomer impurity

IUPAC Name : 2-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-3-hydroxypropyl L-valyl-L-valinate

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Applications : This is an impurity of Ganciclovir, which is a nucleoside analog with antiviral activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir has demonstrated efficacy against human cytomegalovirus infections.

References : Fan-Havard P. et al.: J. Clin. Pharm. Therap.,14, 329, 1989; Faulds D. et al.: Drugs 39(4), 597, 1990.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.