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Valproic acid-d4

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SL-5405

Valproic acid-d4, >98% (HPLC)

Isotopic Purity : 98 atom % D

CAS No. : [87745-17-3]

Synonyms : VPA-d4

IUPAC Name : 2-Propylpentanoic acid-d4

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Chemical Properites
Mol. Formula :
C8H12D4O2
Mol. Weight :
148.24
Appearance :
Colorless oil
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Valproic acid-d4 is a deuterium labelled version of Valproic acid, which is a fatty acid with anticonvulsant properties used in the treatment of epilepsy. It is also a histone deacetylase inhibitor and is under investigation for treatment of HIV and various cancers.

References : Phiel C. J. et al.: J. Biol Chem., 276(39), 36734-41, 2001; Gottlicher M. et al.: EMBO J. 20(24), 6969-78, 2001; Kramer O. H. et al: EMBO J. 22(13), 3411-20, 2003.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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