Valsartan (R)-enantiomer

SL-2387

Valsartan (R)-enantiomer, >98%

CAS No. : [137862-87-4]

MDL No. : MFCD18252868

Synonyms : N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-N-pentanoyl-D-valine; Valsartan USP related compound A

IUPAC Name : (R)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid

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Applications : Valsartan is an angiotensin II receptor antagonist, which is used as a single (S)-enantiomer and the activity of the (R)-enantiomer is clearly lower than the (S)-enantiomer.

References : Patocka J. D. A. et al.: Journal of Applied Medicine, 2, 95–100, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.