Vandetanib-d3 N-Oxide

SL-372

Vandetanib-d₃ N-Oxide, >98% (CP)

Isotopic Purity : 99 atom % D

MDL No. : MFCD28343978

Related CAS No. : [1797030-22-8] of the unlabelled compound

IUPAC Name : 4-(((4-((4-Bromo-2-fluorophenyl)amino)-6-methoxy-d₃-quinazolin-7-yl)oxy)methyl)-1-methylpiperidine 1-oxide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Vandetanib N-Oxide-d3 is the deuterium labelled analog of second major metabolite of Vandetanib N-Oxide, formed during the metabolism of vandetanib via flavin-containing monooxygenase (FMO) polymorphisms FMO1 and FMO3. Exposure to vandetanib N-oxide was very low compared with that of vandetanib and increased exposure to vandetanib N-oxide led to severe hepatic impairment.

References : GiangThy N T. Am. J. Health. Syst. Pharm. 70(10), 849, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term storage.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.