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Vandetanib N-Oxide

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SL-371

Vandetanib N-Oxide, >98%

CAS No. : [1797030-22-8]

MDL No. : MFCD28343977

IUPAC Name : 4-(((4-((4-Bromo-2-fluorophenyl)amino)-6-methoxyquinazolin-7-yl)oxy)methyl)-1-methylpiperidine 1-oxide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG195.00
Back Order  Estimated to ship on 04 October 2026
10MG295.00
Back Order  Estimated to ship on 04 October 2026
25MG595.00
Back Order  Estimated to ship on 04 October 2026
50MG995.00
Back Order  Estimated to ship on 04 October 2026
100MG1695.00
Back Order  Estimated to ship on 04 October 2026
We accept
Chemical Properites
Mol. Formula :
C22H24BrFN4O3
Mol. Weight :
491.35
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Vandetanib N-Oxide is the second major metabolite of vandetanib formed during the metabolism of vandetanib via flavin-containing monooxygenase (FMO) polymorphisms FMO1 and FMO3. Exposure to vandetanib N-oxide was very low compared with that of vandetanib and increased exposure to vandetanib N-oxide led to severe hepatic impairment.

References : GiangThy N. T. Am. J. Health Syst. Pharm. 70(10), 849, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term storage.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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