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Varoglutamstat

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SI-6639

Varoglutamstat, >98% (HPLC)

CAS No. : [1276021-65-8]

Synonyms : PQ-912

IUPAC Name : (S)-1-(1H-Benzo[d]imidazol-6-yl)-5-(4-propoxyphenyl)imidazolidin-2-one

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Chemical Properites
Mol. Formula :
C19H20N4O2
Mol. Weight :
336.4
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Varoglutamstat potently inhibits QC with low‑nanomolar affinity (Ki = 20–65 nM) in human, rat, and mouse systems. This broad activity profile makes it a valuable tool for probing QC‑dependent processes relevant to neurodegeneration.

References : Zhang Y. et al.: Eur. J. Pharmacol, 931, 175178, 2022; Hoffmann T. et al.: J. Pharmacol. Exp. Ther., 362(1), 119-130, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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