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Vazegepant urea impurity

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Vazegepant urea impurity, >98%

Synonyms : Zavegepant urea impurity

IUPAC Name : 3-(7-Methyl-1H-indazol-5-yl)-2-(4-((7-methyl-1H-indazol-5-yl)methyl)-2,5-dioxoimidazolidin-1-yl)propanoic acid

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C23H22N6O4
Mol. Weight :
446.47
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Vazegepant, which is an orally active CGRP receptor antagonist used in migraine research and can also be given intranasally. CGRP plays a key role in migraine pathophysiology.

References : Moreno-Ajona D. et al.: Curr Opin Neurol., 33(3), 309-315, 2020; Gene M. D. et al.: Med Chem., 63(13), 6600-6623, 2020; Capi M. et al.: Springer International Publishing, 67-72, 2022; Jessica Barreto R. D. S. et al.: Eur. J. Pharmacol., 922, 174902, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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