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Vemurafenib

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SI-4332

Vemurafenib, >98% (HPLC)

CAS No. : [918504-65-1]

MDL No. : MFCD18074504

Synonyms : RO5185426; PLX4032; RG7204

IUPAC Name : N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
50MG65.00
Back Order  Estimated to ship on 04 October 2026
100MG85.00
Back Order  Estimated to ship on 04 October 2026
250MG135.00
Back Order  Estimated to ship on 04 October 2026
1G295.00
Back Order  Estimated to ship on 04 October 2026
5G595.00
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C23H18ClF2N3O3S
Mol. Weight :
489.92
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Vemurafenib is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay. 10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold.

References : Ding H. X. et al.: Bioorg. Med. Chem. 21(11), 2795-2825, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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