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CAS No. : [918504-65-1]
MDL No. : MFCD18074504
Synonyms : RO5185426; PLX4032; RG7204
IUPAC Name : N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 50MG | 65.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | 85.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | 135.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 1G | 295.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 5G | 595.00 | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C23H18ClF2N3O3S | Mol. Weight : 489.92 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Vemurafenib is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay. 10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold.
References : Ding H. X. et al.: Bioorg. Med. Chem. 21(11), 2795-2825, 2013.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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