Venetoclax-d8

SL-11813

Venetoclax-d8, >98%

CAS No. : [1257051-06-1]

Synonyms : ABT-199-d8; GDC-0199-d8; RG7601-d8

IUPAC Name : 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl-2,2,3,3,5,5,6,6-d8)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Venetoclax-d8 is a deuterium-labelled version of Venetoclax. This can be used as an analytical labelled reference standard. Venetoclax is a highly potent, selective and orally bioavailable B-cell lymphoma 2 (BCL-2) inhibitor. It is used to treat chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and acute myeloid leukemia (AML).

References : Souers A. J. et al.: Nat Med., 19(2), 202-8, 2013; Peirs S. et al.: Blood 124(25), 3738-47, 2014; Bi C. et al.: Haematologica, 102(4), 755-764, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.